Lab Members

Elizabeth Petri Henske, MD

Elizabeth Petri Henske, MD

Principal Investigator
Read more about Dr. Henske here.

Contact Info:


Karen Forti

Karen Forti

Administrative Assistant

Contact Info:


Jane Yu, PhD

Jane Yu, PhD

Instructor in Medicine
Division of Pulmonary and Critical Care Medicine
Brigham and Women’s Hospital and Harvard Medical School

Contact Info:


Education / Training:

  • Peking University of China (BS- Biology).
  • Graduate School of the City University of New York (PhD, Biochemistry- 1999).
  • Fox Chase Cancer Center, Post-doctoral Fellowship (Henske Lab).

Research Interests:

Dr. Yu has been an investigator in LAM research since 1998. She worked on the characterization of primary cell cultures derived from angiomyolipoma and LAM. She demonstrated that estrogen and tamoxifen stimulate LAM-associated angiomyolipoma cell growth and activate both genomic and nongenomic signaling pathways, and uncovered that estrogen-induced activation of mTOR is mediated via tuberin and Rheb. She currently develops animal models of LAM, studies mechanisms through which tuberin and hamartin regulate estrogen-mediated metastatic phenotypes, and develops estrogen-focused targeted therapeutic strategies for LAM.

Hobbies / Interests:

  • Tennis
  • Basketball
  • Karaoke
Carmen Priolo, MD, PhD

Carmen Priolo, MD, PhD

Instructor in Medicine
Division of Pulmonary and Critical Care Medicine
Brigham and Women’s Hospital and Harvard Medical School

Contact Info:


617-355-9012

Education / Training:

  • University of Messina Medical School, Italy (MD- 2000)
  • University of Messina and Regina Elena Cancer Institute (Medical Oncology- 2004)
  • Catholic University (PhD, Endocrinological Sciences- 2007)
  • Dana Farber Cancer Institute, Harvard Medical School (Postdoctoral Fellowship)

Research Interests:

Dr. Priolo received her PhD from the Catholic University (Rome) in 2007. Her thesis focused on the generation of novel patient-derived pre-clinical models of prostate cancer and was developed at the Dana-Farber Cancer Institute, Harvard Medical School, where she also completed a post-doctoral training.

Dr. Priolo is currently an Instructor in Medicine in the Division of Pulmonary and Critical Care Medicine, Department of Medicine, at the Brigham and Women’s Hospital and Harvard Medical School. Her research focuses on the links between genetic and metabolic alterations in human tumors, with the goal to uncover metabolic dependencies in LAM and TSC that can be targeted therapeutically and exploited to improve diagnostics.

Hobbies / Interests:

  • Cooking
  • Piano
  • Writing Poetry
Douglas Medvetz, PhD

Douglas Medvetz, PhD

Postdoctoral Research Fellow
Division of Pulmonary and Critical Care Medicine
Brigham and Women’s Hospital and Harvard Medical School

Contact Info:


617-355-9103

Education / Training:

  • Walsh University (BS, Biology- 2003)
  • University of Akron (PhD, Inorganic Chemistry- 2008)

Research Interests:

Dr. Medvetz received his PhD in Inorganic Chemistry, focusing on the anticancer properties of silver containing small molecules. Doug is currently working on discovering novel therapies for TSC and LAM via high-throughput screening. He is also investigating the role of Folliculin in the pathogenesis of Birt-Hogg-Dube Syndrome.

Hobbies / Interests:

  • Basketball
  • Weight Lifting
  • Real Estate
  • Beer / Brewing
Damir Khabibullin, MS

Damir Khabibullin, MS

Research Associate / Lab Manager
Division of Pulmonary and Critical Care Medicine
Brigham and Women’s Hospital

Contact Info:


617-355-9105

Education / Training:

  • Kazan State University, Russia (BA- English Translation)
  • Kazan State University, Russia (MS- Molecular Biology)

Research Interests:

Damir is currently working to identify the role and functions of folliculin, as it relates to the pathogenesis of Birt-Hogg-Dube (BHD) Syndrome. He is also developing animal models of FLCN inactivation.

Hobbies / Interests:

  • Computers, computer games
  • Archery
Erik Zhang, PhD

Erik Zhang, PhD

Research Scientist
Division of Pulmonary and Critical Care Medicine
Brigham and Women’s Hospital

Contact Info:


Education / Training:

  • Zhongshan University of China (BS- Biology).
  • Graduate School of the City University of New York (PhD, Biology- 1998).
  • He was trained with Drs. Rembold, Chacko and Fisher in muscle biology.

Research Interests:

Dr. Zhang is currently investigating the role of estrogen-induced inflammation in the pathogenesis of LAM; he is specifically interested in the role of dyregulated expression of COX enzymes and prostaglandins in disease formation and progression. Dr. Zhang is skilled in utilizing bio-informatic methodologies and tools.

Hobbies / Interests:

  • Web design
  • Film / Movies
  • Swimming
Chenggang Li, PhD

Chenggang Li, PhD

Postdoctoral Research Fellow
Division of Pulmonary and Critical Care Medicine
Brigham and Women’s Hospital and Harvard Medical School

Contact Info:


617-355-9129

Education / Training:

  • Harbin Medical University, China (M.M. & B.M)
  • Peking Union Medical College, China (PhD)

Research Interests:

Dr. Li is currently studying the role of estrogen in LAM pathogenesis.

Sun “Sunny” Yang, PhD

Sun “Sunny” Yang, PhD

Postdoctoral Research Fellow
Division of Pulmonary and Critical Care Medicine
Brigham and Women’s Hospital and Harvard Medical School

Contact Info:


617-355-9009

Education / Training:

  • 2001-2005 Shenyang Pharmaceutical University (B.S.)
  • 2005-2010 Peking Union Medical College & Chinese Academy of Medical Sciences (Ph.D.)
  • 2010-2012 Peking Union Medical College (Postdoctoral research fellow)
  • 2012-current Brigham and Women’s Hospital/ Harvard Medical School (Postdoctoral research fellow)

Research Interests:

  1. Metabolic reprogramming in TSC2- null cells
  2. Female hormones and lung injury

Hobbies / Interests:

  • History
  • Sports
  • Travel
Hilaire Lam, PhD

Hilaire Lam, PhD

Postdoctoral Fellow
Division of Pulmonary and Critical Care Medicine
Brigham and Women’s Hospital and Harvard Medical School

Contact Info:


Education / Training:

  • Wellesley College (BA, Biological Chemistry with honors project in the laboratory of T. Kaye Peterman, PhD)
  • University of Pittsburgh, School of Medicine (PhD, Cellular and Molecular Pathology, in laboratory of Augustine MK Choi, MD, Department of Pulmonary, Allergy and Critical Care Medicine)
  • Brigham and Women’s Hospital, Harvard Medical School (Research Associate with Augustine MK Choi, MD, Department of Pulmonary and Critical Care Medicine)
  • Brigham and Women’s Hospital, Harvard Medical School (Postdoctoral Fellow with Piero Anversa, MD, Department of Anesthesia and Medicine)
  • Brigham and Women’s Hospital, Harvard Medical School (Postdoctoral Fellow with Elizabeth (Lisa) Henske, MD, Department of Pulmonary and Critical Care Medicine)

Research Interests:

As an undergraduate researcher, Dr. Lam investigated the Arabidopsis thaliana protein Patellin 1, a lipid binding protein associated with cytokinesis. She received her doctorate in Cellular and Molecular Pathology from University of Pittsburgh, School of Medicine working in the laboratory of Dr. Choi. Her graduate work focused on the regulation of proteostasis by HDAC6 and autophagy in cigarette smoke-induced cilia loss, which contributes to chronic obstructive pulmonary disease (COPD) pathogenesis. As a postdoctoral fellow in the Anversa laboratory, Dr. Lam investigated regenerative and aging mechanisms in heart and lung stem cells. Dr. Lam’s current research is focused on elucidating therapeutically targetable events of metabolic reprogramming in LAM/TSC.

Hobbies / Interests:

  • Reading
  • Baking
  • Kayaking
  • Softball
  • Theology/Philosophy
  • Volunteering
Charilaos Filippakis, Ph.D.

Charilaos Filippakis, Ph.D.

Postdoctoral Fellow
Division of Pulmonary and Critical Care Medicine
Brigham and Women’s Hospital and Harvard Medical School

Contact Info:


617-355-9021

Education / Training:

  • School of Medical Sciences, University of Aberdeen, UK. (B.Sc. Honors, Genetics)
  • School of Medicine, University of Crete, Greece. (M.Sc. Cellular and Genetic Etiology, Diagnosis and Treatment of Human Disease)
  • School of Medicine, University of Crete, Greece. (Ph.D. Biochemistry/Virology)
  • Molecular Oncology Research Institute, Tufts Medical Center, Boston, MA. (Postdoctoral Fellow)
  • Brigham and Women’s Hospital, Harvard Medical School (Postdoctoral Fellow)

Research Interests:

Dr. Filippakis received his Ph.D. from the University of Crete Medical School in 2011. His thesis focused on the involvement of the oncogenic Ras signaling pathway during active human cytomegalovirus infection. Harry then investigated the role of T-antigens of the polyomaviruses SV40 and MCV in tumorigenesis at the Molecular Oncology Research Institute at Tufts Medical Center. His current research focuses on the metabolic vulnerability of lymphangioleiomyomatosis and the tuberous sclerosis complex that could be targeted therapeutically.

Hobbies / Interests:

  • Cooking
  • Reading
  • Travel
Alicia Llorente Lope

Alicia Llorente Lope

Research Trainee
Division of Pulmonary and Critical Care Medicine
Brigham and Women’s Hospital

Contact Info:


617-355-9023

Education / Training:

  • University of Barcelona, Spain. Degree in Biomedical Sciences.

Hobbies / Interests:

  • Piano
  • Cello
  • Scuba diving
  • Travelling